HSS 3106 Chapter Notes - Chapter 23: Neurotransmitter Receptor, Glycinergic, Central Nervous System
23 Feb 2019
School
Department
Course
Professor
Document Summary
Non channel synapses neuroreceeptors are membrane-bound enzymes (not channels: when activated by neurotransmitter, they catalyze the production of messenger chemical inside the cell. Neuromusclar junctions synapses formed btwn motor neurons and muscle cells: always use the neurotransmitter acetylcholine and are always excitatory. Electrical synapses membranes of two cells actually touch and share proteins: allow action potential to pass directly from one membrane to the next, fast but rare, found only in heart and eye. Action potential > synthesis precursor > synthesis of enzyme > packaging > release + (heteroreceptors) > release at synapse > action at receptor > breakdown > reuptake. Types of nt receptors adrenergic, dopaminergic, gabaergic, glutaminergic, histaminergic, cholinergic, opioid, serotonergic, glycinergic. Attention-deficit disorder and adhd treat with amphetamine and methylphenidate. Cns stimulants diverse group of pharmacologic agents; many are prescription drugs: mechanism of action not clear, they stimulate cerebral cortex and increase activity or norepinephrine, dopamine, and other catecholamines at cns synapses.
