BISC 101 Chapter Notes -Resting Potential, Ion Transporter, Cell Membrane

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Glial cells are an important component of the cns 1-5 trillion in human brain. Astrocytes-provide structural support; regulate extracellular concentrations of neurotransmitters. Formation of resting membrane potential- key role of n+ and k+ 1) ion concentrations inside and outside neuron differ 2) concentration gradients exist across the membrane 3) selectively permeable membrane, k+>>>na+ 4) concentration gradients are maintained by na+ k+ pumps. High k and low na inside the cell, low k and high na outside the cell. 1) na/k pump generates and maintains concentration gradients for na and k transporting 3. Na+ out for every 2k+ in 2) little net inward diffusion of na+ due to few open resting na channels 3) significant outflow of k+ due to large number of open resting k channels. Graded potential= small change in membrane potential where magnitude varies with size of stimulus. Action potential= all or none; constant magnitude and can regenerate along axon.

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