PHAR 100 Chapter Notes - Chapter 4: Heart Failure, Combined Oral Contraceptive Pill, Drug Allergy
11 Nov 2016
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Lesson a. 4 drug toxicity and routes of drug administration. List major substances involved in accidental child poisoning. List steps to be taken to minimize accidental child poisoning. Distinguish between the four categories of adverse effects. List reasons why drug toxicity in humans is difficult to predict from animal studies. Explain why dosage of drugs must be adjusted in individual patients. List the advantages and disadvantages of administering drugs by different routes. Majority of accidental poisoning occurs in children under 5 years of age (often acetaminophen or aspirin) The ten most common accidental poisoning items include: acetaminophen, aspirin, bleach, diaper- pail deodorizer, chocolate flavoured laxatives, children"s fever drops, cough syrup, tranquilizers, birth control pills and cigarette butts. Major drugs groups often associated with suicide attempts include barbiturates and similar drugs. Barbiturate tablets were once dispensed as sedatives/sleeping tablets. Current day western society has replaced the barbiturates with benzodiazepine group drugs (ie. diazepam (valium)) as they are a much safer sedative.
