PSYC-2656EL Chapter Notes - Chapter 15: Acetylcholinesterase, Drug Delivery, Bioavailability

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Tyrosine l-dopa dopamine norepinephrine epinephrine. Drug increases the synthesis of neurotransmitter molecules. Drug increase the number of neurotransmitter molecules by destroying degrading enzymes. Drug increase the release of neurotransmitter molecules from terminal buttons. Drug binds to autoreceptors and blocks their inhibitory effect on neurotransmitter release. Drug binds to postsynaptic receptors and either activates them or increase the effect on them of neurotransmitter. Drug blocks the deactivation of a neurotransmitter molecules bu blocking degradation or reuptake. Drug blocks the synthesis of neurotransmitter molecules. Drug causes the neurotransmitter molecules to leak from vesicles and be destroyed by degrading enzymes. Drug blocks the release of the neurotransmitter molecules from terminal buttons. Drug activates autoreceptors and inhibits neurotransmitter release. Drug is a receptor block; it binds to the postsynaptic receptors and blocks the effect of the neurotransmitter. Juglone (found in walnut husks) antagonistic drug. Hemicholinium -3/hc-3 (prevents chlorine from entering neuron) antagonistic.

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