PSYC 2410 Lecture Notes - Lecture 8: Axon Terminal, Autoreceptor, Reuptake

• School: University of Guelph
• Department: Psychology
• Course: PSYC 2410
• Professor: Elena Choleris

Document Summary

Deliberate genetic manipulations (gene knockout and gene knockin) Agonist: a drug that facilitates the effects of a particular neurotransmitter. Antagonist: a drug that inhibits the effects of a neurotransmitter. 7. their neurotransmitter molecules into the synapse released neurotransmitter molecules bind with autoreceptors and inhibits subsequent neurotransmitter release released neurotransmitter molecules bind to postsynaptic receptors released neurotransmitter molecules are deactivated either by reuptake or enzymatic degradation. Drug increases the synthesis of neurotransmitter molecules (e. g. by increasing the amount of precursors) Drug increases the number of neurotransmitter molecules by destroying degrading enzymes. Drug increases the release of neurotransmitter molecules from terminal buttons. Drug binds to autoreceptors and blocks their inhibitory effect on neurotransmitter release. Drug binds to postsynpaptic receptors and either activates them or increases the effect on them or neurotransmitter molecules. Drug block the deactivation of neurotransmitter molecules by blocking degradation or reuptake. Drug blocks the synthesis of neurotransmitter molecules (e. g. by destroying synthesizing enzymes).