EXCI 251 Chapter Notes - Chapter 4: Myocyte, Myofibril, Red Color

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silvermink789

15 Mar 2018

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4. 1 basic muscle physiology and the effects of strength training. Muscles make up more than 40% of your body mass. You depend on your muscle for movement and because of their mass, they are the site of a large portion of the energy reactions that take place in the body. Muscular strength is the ability to generate force during a maximal efforts. Muscular endurance is the ability to resist figure while holding or repeating muscular contraction for a long time. Muscles move the body and enable it to exert force because they move the skeleton. When a muscle contracts (shortens), it moves a bone by pulling on the tendon that attached the muscle to the bone. When a muscle relaxes (lengthens), the tension places on the tendon is released and the bone moves back to or closer to its starting position. Muscle physiology: muscles consist of individual muscle fibers (aka muscle cells) that are connected in bundles.

Related Questions

Answer question part a-d

Question part A

Diffusion Lab

Purpose: To investigate the diffusion of a substance across a semipermeable membrane.

Materials:

iodine (must be colored, clear won't work)

cornstarch/water solution

plastic sandwich bags (cheap is good)

beakers or clear plastic cups

Set-Up and Procedure
1. Fill beaker about halfway and put about ten drops of iodine.
2. Put about a teaspoon of starch and about 3 ounces of water in baggie and tie.
3. Make sure that it is water tight
4. Put the baggie in the beaker or glass and wait.
5. In about 15 minutes the solution in the baggie will turn blue/black. (purple)
This is a result of the iodine diffusing through the bag.
You should know that iodine is an indicator for starch. It turns blue/black in color.
Test it by dropping some iodine on a piece of white paper.

Questions and Conclusions :

Define permeability

To which substance is the plastic bag is permeable ?

Why did the iodine enter the bag ?

Why didn't the starch enter the beaker?

How is the plastic bag like the cell membrane?

Question part b

Reflex Lab

Procedures for Reflex Lab

In this lab we will test muscle stretch reflexes and cutaneous reflexes.

A partner is needed to be the subject for this lab.

Purpose: To test and observe normal muscle stretch and cutaneous reflexes.

Equipment: Reflex hammer,

Background: In the most narrow sense, a reflex is an involuntary, unpremeditated response by the body to an external stimulus. Reflexes allow reaction to a stimulus more quickly than would be possible if conscious thought were involved. A reflex can be described as a stimulus-response cycle. Most reflexes involve the brainstem or the spinal cord and do not require interaction from higher brain centers. The muscle stretch reflexes are the simplest reflexes. They involve the sensory neuron synapsing directly upon the motor neuron. They are sometimes called monosynaptic reflexes. They are also called spinal reflexes because the reflexive action does not require input from the brain. The other reflexes we will be testing in this lab are the cutaneous reflexes. They are also called superficial reflexes because the receptors are in the superficial areas of the body. They are more complex and require the message to go up the spinal cord to the brain and then back down to elicit the response. These can be used to test for CNS injury.

There are five components to a reflex; these components together are called the reflex arc. The components are as follows:

sensory receptor â receives the stimulus and generates an impulse (is usually a nerve ending)

afferent pathway â a neuron that carries the impulse from the receptor to a central integrating center

integrating center âthis is where the afferent component connects to the efferent component- this is in the CNS. One or more synapses must occur here. Interneurons are not involved in stretch reflexes but are always found in all other types of reflexes.

efferent pathway - a neuron that carries the impulse from the integrating center to an effector.

effector -receives the impulse and responds. The effector may by skeletal muscle, smooth muscle, or glands.

For more information please read chapter 12 : "Muscle" ( Pages 380-390) in Human Physiology book ( 12th edition by Stuart Ira Fox)

Part I. Stretch reflexes.

First do muscle stretch reflexes which are also called deep tendon reflexes.

It is important the subject relax the muscle being tested. Tell the subject to let the muscle go limp.

Rate each response according to the following scale:

+4 very brisk, hyperactive, large movement at joint.

+3 brisker than average, medium movement at joint

+2 average, small movement at joint

+1 somewhat diminished, very small or no movement at joint

0 no response

A. Patellar (also called the knee jerk reflex) â activation of femoral nerve. The receptor is located in the quadriceps muscle, the effector is the quadriceps muscle. The nerve ending is responding to the stretch of the muscle caused by striking the tendon.

1. A subject is allowed to sit comfortably on a table with knees dangling over the edge.

2. Using a reflex hammer (or substitute as described above) strike the patellar tendon just below the kneecap.

3. Observe the action caused by the reflex.

4. Record your results using the graded scale above.

B. Biceps Reflex â activation of the musculocutaneous nerve

1. Rest subjectâs left forearm along your left forearm.

2. Subjectâs hand should rest in or near the bend of your elbow.

3. Press your left thumb on the subjectâs biceps tendon, apply a little pressure.

4. Strike your thumb with the reflex hammer, this will transfer the pressure to the biceps tendon.

5. Watch carefully for twitching of the biceps muscle. Usually, the forearm will not move.

6. Record your results using the graded scale above.

C. Triceps reflex â activation of the radial nerve.

This is a difficult reflex to observe, but give it a try.

1. The subject should have the arm relaxed and elbow bent.

2. Support the entire weight of the arm with your left hand.

3. Strike the triceps tendons, just above the elbow.

4. Watch carefully for twitching of the biceps muscle.

5. Record your results using the graded scale above.

Both B and C show up best on someone who doesnât have a lot of subcutaneous fat and who has good muscle definition.

D. Achilles reflex (also called ankle-jerk reflex) â activation of the poplitealnerve. The principle is similar to the knee-jerk reflex. Here the stretch receptors are located in the gastrocnemius muscle.

1. Have the subject take her/his shoes and socks off, exposing the Achilles tendon on the back of the ankle.

2. Strike the Achilles with the reflex hammer (or substitute) and observe the extension of the foot downward.

3. Record the results using the graded scale above.

Part II. Cutaneous reflexes

A. Plantar reflex

This reflex differs from the four muscle stretch reflexes. In this reflex, receptors are stimulated in the sole of the foot (cutaneous receptors). The reflex pathway travels up the leg to the integrating center. While in the integrating center, the reflex travels up the spinal cord through the pyramidal tracts, which are nerve pathways between the spinal cord and brain.

1. The subject needs to lie on his or her back, with shoes and socks off.

2. Using the end of the handle of the reflex hammer, trace a path along the lateral side from heel to the little toe to the big toe.

3. Observe for the flexion (toe curling) which is recorded as a normal plantar reflex.

4. If the toes curl, this is called a Negative Babinski response and is normal. If the toes flare, then an abnormal response is recorded and is called a Positive Babinski response and indicates CNS damage.

5. Record the results.

B. Ciliospinal reflex â This reflexive pathway is from the skin to the thoracic spinal cord, through the sympathetic trunk, then to the dilator pupillae muscle of the eye. This is another test of the CNS.

1. Pinch the back of the subjectâs neck,

2. Watch pupils for a response.

3. A normal response is dilation of the pupil.

4. Record your results.

question part c

Homeostasis Lab - Heart Beat Regulation

This lab is designed to help explore the process of homeostasis as it applies to regulating heart rate. It also should help how a sampling process works.

Make two copies of the data sheet (or make your own) and paste them into your report.

1. Take a pulse for six seconds, record this number in the table below.

2. Every 15 seconds for the next three minutes, take a pulse again for six seconds, record each of these values.

3. Multiply each of these values by 10 to get the beats per minute.

4. Now average these numbers (this is the setpoint for the pulse at resting). Note the range of values (that is how far they can deviate from the set point).

5. The next step is to take a 30 second reading. Multiply this number by 2 to get beats per minute.

6. How does this compare to the setpoint?

7. Repeat steps 1 through 6 after running in place for 30 seconds. Record the same data.

8. After getting 8 readings, stop and plot these numbers on a piece of graph paper. The X-axis should be minutes and the Y-axis should be heart rate.(Don't forget to connect the points ). You can do this in Excel and then import it into Word. Or you can e-mail this to me.

Submit your lab report in the correct format.. Respond to the questions above. Explain WHY the results were what they were. Compare the resting and post-exercise and postulate explanations for the differences. You should have two data tables and one graph with your heart rate data from both tables on it in your report.

Time in seconds	Heart rate (bpm)
0 (initial recording)
15
30
45
60
75
90
105

question part d

What was one thing you found interesting, confusing or surprising about any of the lab activities? Why?

[email protected]

Tue 9/19/2017 4:17 PM

To:

[email protected];

Here is the exam review for our next major lecture exam which will be on Monday. Notice that there are a few things missing, such as endochondral ossification. These will be added so just because it does not show up on this exam review doesn't mean you shouldn't study it. That being said, the details of each and every bone which I've gone over in lecture will be on the lab practical rather than the written lecture exam.

Anat 1, Exam 2. Spr 2016 LASC Name:____________________________________________________

1) A synarthrosis: a) is filled with synovial fluid. b) allow for a wide range of movement. c) includes the squamosal suture. d) is exemplified by the shoulder. e) all of the above.

2) Bursae: a) are located in the right atrium. b) are like elastomeric shock absorbers. c) are found in skeletal muscle fibers. d) form the sarcoplasmic reticulum. e) none of the above.

3) Irregular bones: a) can act like cams. b) can provide sites for muscle attachment. c) can protect soft-tissue organs. d) can act as levers. e) all of the above.

4) Condyles: a) are smooth articular surfaces. b) allow blood vessels to enter the bones. c) occur beneath the nail body after an injury. d) are produced by infected sebaceous glands. e) none of the above.

5) A head: a) is where you will find hyaline cartilage. b) is a smooth articular surface. c) is where a bone meshes with another bone. d) all of the above. e) none of the above.

6) Which of the following is the proper sequence of things following a bone fracture: a) hematoma, fibrous callus, bony callus, remodeling. b) hematoma, bony callus, fibrous callus, remodeling. c) hematoma, remodeling, fibrous callus, bony callus. d) hematoma, remodeling, bony callus, fibrous callus. e) fibrous callus, bony callus, remodeling, hematoma.

7) A diaphysis: a) contains yellow bone marrow. b) contain a lot of spongy bone tissue. c) occurs at the ends of long bones. d) all of the above. e) none of the above.

8) Short bones: a) protect underlying soft tissue organs. b) include the ribs. c) include the cranial bones of the skull. d) transfer mechanical forces. e) all of the above.

9) Fibrous joints: a) contain cruciate ligaments. b) include the pubic symphysis. c) are typically found in third class levering systems. d) include the lambdoid suture. e) all of the above.

10) Which of the following doesnât belong? a) tibiofibular joint. b) dentino-alveolar joint.
c) intervertebral disc. d) radioulnar articulation. e) cartilage.

11) Which of the following doesnât belong? a) atlanto-occipital joint. b) humero-ulnar joint. c) frontal suture d) acromio-humeral joint. e) tibiotarsal joint.

12) Hyaluronic acid: a) forms the extracellular matrix. b) is found in fibrous joints. c) keeps cartilage soft and pliable. d) is found in synostoses. e) none of the above.

13) First class levers: a) include the tibio-tarsal joint. b) have the effort between the fulcrum and the load. c) are like a teeter-totter. d) all of the above. e) none of the above.

14) Synchondroses: a) are typically synovial joints. b) allow for very limited movement. c) include sutures and gomphoses. d) are encased in synovial capsules. e) none of the above.

15) Parallel muscles: a) have long excursions. b) include the abdominal muscles. c) have excellent endurance. d) have low strength. e) all of the above.

16) Sphincteral muscles: a) enclose openings or passageways. b) are used when you talk.
c) surround the eyes. d) include the orbicularis oculi. e) all of the above.

17) Pennate muscle architecture: a) is typified by the pectoralis major. b) have high endurance.
c) generates high strength. d) has a longer excursion. e) all of the above

18) Endomysium: a) consists of dense fibrous connective tissue. b) surrounds each fasciculus.
c) surrounds bundles of muscle cells. d) all of the above. e) none of the above.

19) Cartilage: a) heals quickly if it is damaged. b) forms the lining of blood vessels. c) is found on the articular surfaces of bones. d) is a type of epithelial tissue. e) none of the above.

20) A tuberosity: a) is a hollow opening. b) is a shallow smooth articular surface. c) is a raised area that adjoins a condyle. d) is a larger outwardly curved articular surface. e) is a raised, rough-textured area.

21) Which of these doesnât belong? a) tuberosity b) trochanter c) condyle d) tubercle e) lunula

22) Epimysium: a) wraps around the entire muscle. b) is made of dense fibrous connective tissue. c) is continuous with tendons. d) all of the above. e) none of the above.

23) Which of the following is more likely to be an insertion rather than an origin? a) ulna.
b) cervical vertebra. c) thoracic vertebra. d) rib. e) Ischium.

24) Which of the following is more likely to be an origin rather than an insertion? a) clavicle.
b) tibia. c) radius. d) ulna. e) metatarsal.

25) Myofibrils: a) are composed of many muscle fibers. b) are composed of many muscle cells.
c) are composed of many sarcomeres. d) form the endomysium. e) all of the above.

26) Myosin: a) helps keep muscle cells from overstretching. b) is a protein. c) joins thin filaments together. d) forms part of the z-disc. e) all of the above.

27) Sarcolemma: a) surrounds the entire muscle organ. b) surrounds the endomysium.
c) is the cell membrane of a muscle fiber. d) surrounds the epimysium. e) none of the above.

28) Thin filaments: a) are made of titin. b) are pulled on by the thick filaments during contraction.
c) create the molecular âpower-strokeâ. d) all of the above. e) none of the above.

29) A second class lever: a) is like a wheel barrow. b) is like a teeter-totter. c) describes the humeroulnar joint. d) describes the atlanto-occipital joint. e) none of the above.

30) A sarcomere: a) is the basic unit of muscle function. b) is made mostly of proteins. c) shortens during a contraction. d) delivers an âall or noneâ response. e) all of the above.

31) Fast glycolytic fibers: a) have excellent endurance. b) deliver lots of power.
c) are more reddish in color than oxidative fibers. d) none of the above. e) all of the above.

32) Which of the following doesnât belong? a) Vastus lateralus. b) Vastus intermedius. c) Vastus medialis. d) Rectus Femoris. e) Gluteus minimus.

33) Which of the following doesnât belong? a) Teres major. b) Teres minor. c) subscapularis.
d) infraspinatus. e) supraspinatus.

34) Tendon sheaths: a) are filled with synovial fluid. b) can be likened to brake and shifter cable sheathing on a bike. c) are found around the carpal bones. d) really make life unpleasant if they get inflamed. e) all of the above.

35) Epithelial tissues: a) function in movement. b) conduct electrical impulses. c) form a structure for attachment of other organs. d) form barriers and walls. e) all of the above.

36) Elastic connective tissue: a) is found in bone. b) lines the inside of the trachea. c)Is found in small blood vessels like capillaries. d) is found in large arteries. e) all of the above.

37) Cartilage: a) heals quickly if it is damaged. b) forms the lining of blood vessels. c) is found on the articular surfaces of bones. d) is a type of epithelial tissue. e) none of the above.

38) Dense regular connective tissue: a) is poorly vascularized. b) heals slowly if at all. c) forms tendons and ligaments. d) can look a lot like smooth muscle under the microscope. e) all of the above.

39) Transitional epithelium: a) lines the urinary bladder. b) lines the blood vessels. c) contains cilia. d) joins the epidermis to the dermis. e) none of the above.

40) Skeletal muscle: a) responds to conscious thought. b) is found in the heart. c) is found in the walls of blood vessels and the GI tract. d) is composed of very small cells. e) all of the above.

For the following matching questions, each choice is used only once.

41) Fibroblast a) maintains bone tissue
42) Mast Cell b) secretes mucus
43) Chondrocyte c) responsible for inflammation response
44) Osteocyte d) makes collagen fibers
45) Goblet Cell e) maintains cartilage

For the following true-false questions, mark âAâ for true and âBâ for false.

46) Simple cuboidal epithelium is lines the trachea and Fallopian tubes/oviducts.
47) Elastic cartilage joins the ribs to the sternum.
48) An insertion is the more movable point of muscle attachment.
49) Tendons connect muscle to muscle or bone to bone.
50) Ligaments connect muscle to bone.
51) Transverse tubules allow nutrients to be dispersed throughout very large muscle cells.
52) Muscle twitch occurs when only a few muscle cells in the entire muscle are fully contracted.
53) Slow oxidative fibers have poor strength but excellent endurance.
54) Muscles can lengthen under their own power as well as contract.
55) Pottâs fracture is typical of skateboarders.
56) An incomplete fracture is a complete break through the entire bone.
57) Tetanus is the recruitment of additional fibers during muscle contraction.
58) Menisci are like elastomeric shock absorbers.
59) Diarthrotic joints allow for little to no movement.
60) A belly is the contractile portion of a muscle.
61) Synergistic muscles work with each other.
62) Muscle tissue, like your lab instructorâs evil twin before his morning coffee, is irritable.

redbutterfly464

What is the difference between the study of kinematics and kinetics in regard to forces?

What three components that make up the musculoskeletal âsystemâ.

The musculoskeletal system is composed if many simple machines. There are 4 potential uses for these simple machines, list 2 of these uses.

Fill in the blank a _________ is used to alter the resulting direction of the applied force.

In the body what component acts as a lever and what acts as the axis?

When we think of a lever set up, what does FAR refer to?

Draw a basic F.A.R for each of the following and give an example of where in the body you may find each.

First class lever:

Second class lever:

Third class lever:

Which class of levers is designed best for speed and range of motion and which is best for strength?

What forces determine amount of torque in a system?

A. How much torque needs to be produced to move 60 kg (R) when the RA is 0.30 m and the FA is 0.1 meters?

b. What value could you change to decrease the torque needed to lift the SAME object.

c. Draw the F.A.R unit (say an arm lifting a bucket) label the elements and explain why what you changed in b would decrease torque needed.

12. a. What is the âcontractileâ unit of muscle called? ______________

b. what is the non-contractile element (series elastic element) in a muscle lever system?

13. in regards to âpowerâ which is more powerful, muscle fibers arranged in Parallel or bipennate muscles? ___________

Why?

14. When weight lifting with the goal of increasing strength, what physical characteristic of the muscle are you changing to bring about that increased strength? __________________

15. What is the branch of FDA that controls regulation of medical devices? ____________

16. Which of the following statements is false?

A device can be an instrument or an apparatus.

A device can be something used to diagnose a disease

A device can change the chemistry of your cells

A device can be something that delivers a drug to your body

17. Give one example of a..

Class I device

Class II device

Class III device

18. Which of the following is true regarding device classification?

Devices with the least risk to the patient are considered Class III

A class III device has a high risk potential to the patient

Class III devices are the easiest to get approved

Testing devices on humans is easy and follows no specific guidelines

19. Explain the difference between Harm and Risk.

20. What is a âsubstantial equivalentâ? Is it easier or harder to get approval for a Device that has an SE?

21. Which of the following would not be a priority when developing a medical device?

Cost

Ergonomics

Ease of sterilization

Material

None of the above

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EXCI 251 Chapter Notes - Chapter 4: Myocyte, Myofibril, Red Color

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