Biology And Biomedical Sciences BIOL 2960 Midterm: Sp18 L24-26 Guide
6 Feb 2019
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Study guide 10: gene structure, bacterial transcription, and the genetic code (lectures 24-26) At the end of this unit, you should be able to define and/or use the following terms and concepts: Transcription: dna, mrna, rna polymerase, ribonucleic acid, template strand, non-template (a. k. a. coding) strand, unwinding/rewinding of double stranded dna, initiation, elongation, termination, bacterial transcription initiation, promoter, promoter consensus sequence, 10 and -35 regions of the promoter, transcription start site: rna polymerase subunits: a, b, b", s (sigma), holoenzyme, core enzyme, formation of transcription bubble, bacterial transcription elongation, 5"->3" directionality of mrna synthesis, 3"oh of ribose, phosphodiester bond: bacterial transcription termination, intrinsic termination (rho-independent), hairpin loop. Bacterial transcription regulation: positive regulation, negative regulation, promoter, operator, activator binding site, repressor, activator, rna polymerase, allosteric regulation, inducers (allosteric effectors) Genetic code: triplet code, codon, redundancy, synonymous codons, start codon, stop codons, reading frame. Define and diagram a gene; identify the role of each component part of a gene.
