BIOL 2100 Study Guide - Midterm Guide: Semiconservative Replication, Deoxycytidine Triphosphate, Thymidine Triphosphate
Document Summary
1 prime position is where base is linked to sugar, count moving opposite; know numbering. Nucleic acid polymerization goes from 5" to 3". Old end of a nucelid acid is 5", new end is 3". Conservative replication: (photocopy) entire copy of original strand of dna. Energy of synthesis is with each incoming nuceleotie (tri phosphate group); adds on to existing. A polymerase can move in the opposite direction but it is not synthesizing, but breaking down. Both rna and dna polymerase require template strand. Dna polymerases require a primer in addition to template and nucleotides; polymer must be pre existing; primers extend templat e. Rna polymerases do not require a primer, if a template and nucleotides are present it can begin synthesizing. Dna polymerase reads in one direction, and synthesized in the other. Telomerase enzyme contains rna template that allows the template strand to be lengthened by telomerase repeats. Telomerase folds into globular secondary structure forming chromosome; protects ends.
