NURS 165 Study Guide - Final Guide: Toxic Megacolon, Ileostomy, Octreotide
Intestinal Failure Drugs
Drug
MOA
Indication
Side Effects
Other
Octreotide
somatostatin
receptor agonist,
normalize levels of
GH and IGF
acromegaly, carcinoid tumors,
VIPomas, diarrhea r/t
hypersecretion
hypo/hypergly., hypothyroid,
gallstones/biliary sludge
pruritis
interacts cyclosporine,
insulin, hypoglycemic agents,
...
Loperamide
opioid agonist at
the GI tract, treats
diarrhea and
decreases volume
of output for
ileostomy
diarrhea, high output ileostomy
N/V, dry mouth, abdominal
discomfort, constipation,
toxic megacolon
contraindication infectious
etiology suspected
Teduglutide
GLP2 analog->
improves
absorption
(fluid>nutrients)
parenteral support-dependent
adult patients with short bowel
syndrome
fluid overload, nausea,
abdominal pain, headache,
neoplastic growth
injection site rXN
interacts can inc. GI
absorption of other
medication
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