BIBB 270- Final Exam Guide - Comprehensive Notes for the exam ( 28 pages long!)
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Chapter 5 catecholamines: general information, catecholamines include, dopamine (da, norepinephrine (ne, epinephrine (epi, they belong to the group of neurotransmitters called monoamines (or biogenic amines, monoamines consist of three classes of neurotransmitters, catecholamines, histamine. In lab animals, increased locomotor activity occurs: at higher doses, this is replaced by stereotyped behaviors intense sniffing, repetitive head and limb movements, licking, and biting, stems from increasing stimulation of da receptors in the nucleus accumbens and striatum. Reuptake: da and ne move from the synaptic cleft into the nerve terminal via specific membrane transporter proteins (dat and net, the molecules are then repackaged into vesicles (via vmat) or broken down (via. Adhd selectively block ne transporters: cocaine inhibits reuptake of all the monoamine transmitters: da, ne, and, 2. It gives rise to one pathway: 1) nigrostriatal tract axons from the a9 cell group in the substantia nigra extend to the caudate-putamen (striatum, the a10 cell group is in the ventral tegmental area (vta).