PSYCH 330 Study Guide - Midterm Guide: Neurochemistry, Prolactin, Dopaminergic Pathways
7 Sep 2016
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Neural communication: within neurons: electrical, between neurons: chemical, synapses are chemical connections. Presynaptic membrane: has lots of mitochondria: gives energy in the form of atp, has lots of golgi bodies: package neurotransmitters into synaptic vesicles, each vesicle contains tons of nt"s, terminal button is lled with synaptic vesicles. Postsynaptic membrane: contains the postsynaptic density, dense because of all the neurotransmitter receptors. Ionotropic: ligand-gated ion channel: fast, as soon as nt binds, channel opens up, short. Metabotropic: g-protein coupled receptor: slow, within postsynaptic neuron, requires a lot of energy, effects last for a longer time, 80% of receptors are metabotropic, g proteins open other ion channels or activate second messenger pathways. Reuptake: entire nt molecule is taken back into presynaptic cell via a transporter protein: this removes the nt from the cleft so that we are no longer activating the receptor, take one molecule of nt at a time.
