HTHRHSC 5510 Study Guide - Final Guide: Nitric Oxide, Hair Loss, Glycogen

• School: Ohio State University
• Department: Health and Rehabilitation Sci
• Course: HTHRHSC 5510
• Professor: All

Document Summary

Disease affects the body at the cellular level. What is the goal of the body as it responds to a stressor: to protect normal structure and function of body. Whe(cid:374) st(cid:396)esso(cid:396)s (cid:272)o(cid:374)ti(cid:374)ue o(cid:396) o(cid:448)e(cid:396)(cid:449)hel(cid:373) (cid:272)ellula(cid:396) fu(cid:374)(cid:272)tio(cid:374) : maladaptive changes occur (pathology) leading to morbidity and/or mortality. Storage of products in abnormal amounts (i. e. , calcium salts) How do cells adapt to changes in the internal environment: cells change in size, number, or type (form) Caused (cid:271)(cid:455) disuse, de(cid:374)e(cid:396)(cid:448)atio(cid:374), loss of endocrine stimulation, inadequate nutrition, and ischemia (decreased blood flow). More efficient functioning to reduce oxygen consumption. Example: fracture of distal radius/ulna with casting x6 wks from hand to elbow. Immobilization with workload decline results in decrease in oxygen consumption and protein synthesis. Reduced synthetic processes increased proteolysis (breakdown of proteins or peptides into amino acids) Heart increase cell size due to biomechanical/stretch sensitive mechanism or neurohumoral (hormones) Adaptive: thickening of urinary bladder from long continued obstruction.