NURSE-UN 1436 Midterm: PHARM - Exam 1 - Named Drugs
14 Nov 2018
School
Department
Course
Professor
Document Summary
Medication names you will see on the exam. The thiazide drug hydrochlorothiazide has been combine with selected angiotensin-converting enzyme (ace) inhibitors, beta- blockers, alpha-blockers, angiotensin ii blockers, and centrally acting sympatholytics to control hypertension. Chart 43-1 outlines the pharmacologic data for hydrochlorothiazide. Pharmacokinetics (cid:1694)(cid:1693) thiazides are well absorbed from the gastrointestinal (gi) tract. The half-life of the thiazide drugs is longer than that of the loop diuretics. For this reason, thiazides should be administered in the morning to avoid nocturia (nighttime urination) and sleep interruption. Pharmacodynamics (cid:1694)(cid:1693) thiazides act directly on arterioles to cause vasodilation, which can lower blood pressure. Other action includes the promotion of sodium chloride and water excretion, resulting in a decrease in vascular fluid volume and a concomitant decrease in cardiac output and blood pressure. The onset of action of hydrochlorothiazide occurs within 2 hours. Peak concentration times are long (3 to 6 hours).
