BIOL 2299 Study Guide - Midterm Guide: Pneumocystis Jirovecii, Stephen Jay Gould, Robert Gallo
Document Summary
Smaller protein combine to form mature hiv = virulent. First report of aids was in mmwr june 5 1981 cluster of gay, males in los angeles with unusual pneumonia pneumocystis carinii (pcp) This fungal disease was completely unexpected - essentially never found in healthy, young people. Also kaposi"s sarcoma a rare skin cancer. after publication - similar results came in from other parts of the country: by the end of the year 270 cases 121 deaths. Jan 1982 cdc used the term aids for acquired immunodeficiency disease seems to be an infectious problem with the immune system. Discovery of hiv (announced march 1983: luc montagier at pasteur institute, robert gallo at nih isolated the same virus- found that it grows in immune cells. Development of an elisa test for virus proteins (and a western if necessary) allowed checking of the blood supply: reasonable to expect a vaccine soon but we still don"t have one.