CHE 211 Study Guide - Midterm Guide: Centrifugation, Prentice Hall, Organic Compound
Organic Chemistry 2 – Chemical Purification & Separation
Introduction
• Organic Laboratory Techniques by Fessenden and Fessenden, 3rd edition; Brooks/Cole
Publishers; ISBN: 0-534-37981-8.
• Advanced Practical Organic Chemistry by Leonard, Lygo, and Procter, 2nd edition;
Blackie Academic & Professional; ISBN:0-7514-0200-1
• Techniques in Organic Chemistry by Mohrig, Hammond, Schatz, and Morrill, 2nd edition;
Freeman Publishers; ISBN: 0-7167-6638-8.
• The Student’s Lab Companion by Lehman; 1st edition; Prentice Hall Publishers; ISBN:0-
13-017867-5
Basic Techniques
After the chemical reaction is completed, the chemist needs to separate the organic compound
from the reaction mixture --> after the separation, it needs to be purified
Separation Technique
- Extraction: this is the most common method for separation
Purification Techniques
- Centrifugation
- Crystallization
- Sublimation
- Distillation
- Chromatography
Extraction
The process of transferring a substance from a liquid or a solid mixture to solvent -->
known as EXTRACTION
The solvent used in an extraction is called an extracting solvent
Two main uses of Extraction:
To remove an organic compound from a reaction mixture
To remove impurities from an organic compound that is dissolved in an organic
solvent
Liquid-liquid extraction: Involves the distribution of a solute between two immiscible
liquids
o Liquid-liquid extraction is the most common type of extraction used in chemistry
labs
o The "solute" is the ORGANIC compound
o Solute = the substance dissolved in the solvent (usually present in the smaller
quantity, solvent is the larger quantity)
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Organic chemistry 2 chemical purification & separation. Introduction: organic laboratory techniques by fessenden and fessenden, 3rd edition; brooks/cole. Publishers; isbn: 0-534-37981-8: advanced practical organic chemistry by leonard, lygo, and procter, 2nd edition; Blackie academic & professional; isbn:0-7514-0200-1: techniques in organic chemistry by mohrig, hammond, schatz, and morrill, 2nd edition; Freeman publishers; isbn: 0-7167-6638-8: the student"s lab companion by lehman; 1st edition; prentice hall publishers; isbn:0- After the chemical reaction is completed, the chemist needs to separate the organic compound from the reaction mixture --> after the separation, it needs to be purified. Extraction: this is the most common method for separation. The process of transferring a substance from a liquid or a solid mixture to solvent --> known as extraction. The solvent used in an extraction is called an extracting solvent. To remove an organic compound from a reaction mixture. To remove impurities from an organic compound that is dissolved in an organic solvent.
