NURS 305 Quiz: HELPFUL PHARM HINTS

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4 Apr 2016
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Tells us how the drug influences target cells and causes subsequent changes in the body"s biochemical processes. Affected by the number of receptor cells present. Pharmacokinetics: how the drug moves through the body; adme. Absorption: iv is the best, then im, then sq, then po. Distribution: affected by nutritional status, because most drugs are protein bound (especially albumin) Metabolism: mostly in the liver, so we need them to have a decently functioning liver. Check bun and creatinine if drug is excreted by the kidneys. Penicillins (except nafcillin, because it isn"t excreted by the kidneys) Drink lots of water with these to prevent nephrotoxicity. >if you"re looking for nephrotoxicity, look at serum creatinine and bun. >if they"re elevated, and taking one of the above drugs, possible nephrotoxicity. Other drugs that aren"t antimicrobials that are nephrotoxic include diuretics, radiocontrast dye for ct scans and such, valacyclovir, acyclovir, capreomycin, and polymixin b) Think teenage mutant ninja turtles (tmnt) are bad ass (ba)