NEUROSCI 101 Study Guide - Final Guide: Glucocorticoid Receptor, Corticosterone, Anterior Pituitary
15 May 2016
School
Department
Course
Professor
Document Summary
Epigenetics: mechanism for regulating gene activity independent of dna sequence that determines which genes are turned on and off: waddington. Knew there was some form of genetic control. Realized importance behind what genes are turned on/off during development. Hippocampal involvement with stress response: many glucocorticoid receptors (for cortisol, involved in negative feedback loop that reestablishes homeostasis after stress. Glucocorticoids released (hypothalamus crf anterior pituitary acth. Signals hypothalamus to stop releasing crf . Signals pituitary to stop releasing acth . **less adrenal cortisol is released = homeostasis/recovery from stress*: why are there more glucocorticoid receptor in the hippocampus of offspring of high licking and grooming mother rats? (explain the mechanism) Explain an experiment that supports the view that maternal care may also influence hippocampal glucocorticoid receptors and their methylation. Correlation between behavior and # grs in hippocampus . Long term stress leads to poor behavioral strategies.
