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CAS BI 203 Study Guide - Midterm Guide: Cdc25, Oncogene, Somatic Cell Nuclear Transfer

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burgundyyak766
2 Jan 2017
School
Boston University
Department
Biology
Course
CAS BI 203
Professor
Kenneth Adams

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Document Summary

Mcm helicase cyclin and cdk when it enters m phase it is a helicase and it unwinds the dna from replication, when it gets triggered there is no other start of the cell cycle because you. Integrin signaling don"t really need to know, Titin when you have contraction and relaxation, the titin prevents it from being pulled too much. With actin, there is nebulin that makes sure actin is the proper length. Cyclin and cdk enter the cell cycle but know mpf so you have cyclin b. Cyclin is degraded to get out of mitosis. Don"t need to know the start example of yeast budding but know the restriction point. Don"t need to know hemopoeitic therapeutic cloning with bone marrow human in hospital bed induced pluoropotent stem cells apoptosis. P53 is phosphor when dna damage to cause cell cycle arrest.

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Related Questions

not too details, just main points please...

1. What you should know about microtubles

- MT structure, what they are made of

- MT function

- Motor proteins(kinesins&dyneins)

- How kinesins move, coupling to ATP hydrolysis

- Microtubule Organizing Center (MTOC), how MTs are nucleated

- MT dynamics, how it's affected by drugs and MAPs

- dynamic instability and how its linked to GTP/GDP cycle

- cilia/flagella, axoneme structure

- how cilia/flagella move and the role of dynein

-intra-flagellar transport

2. What you should know about actin filaments

- F-actin structure

- F-actin Function

- Motor proteins (myosins)

- Actin dynamics, how it's affected by actin-binding proteins

- the concept of critical concentration

- actin/myosin structure and function in the contezt of muscle

- how muscle contract

- actinomyosin cycle (myosin movement), coupling to ATP hydrolysis

- How cells move and change shape, using actin

3. What you should know about IF

- IF strcuture, what they are made of

- IF function, roles inside and outside cells

- Regulation of nuclear IF in the cell cycle

- be able to compare major features of IF, Actin, and MTs

Bacterial cytoskeleton, that bacteria have proteins that

- polymerize

-affect cell shape, cytokinesis, ect.

- play analogous roles to MT, F-actin

4. what you should know about the cell cycle

- parts of the cell cycle, stages of mitosis

- MPF; how it was identified, what it is made of (cyclin and cdk)

- Universality of cyclin/Cdks (in yeast, frogs, etc.)

-how Cdk activity is regulated (many mechanisms)

- how Cdks function (by phosphorylation)

- how multiple cdks divide their function

- how the spindle is formed and mistakes corrected

- the role of motors and MY dynamics in above

- the tolr of proteolysis in mitotic transitions

- what a checkpoint is

- how checkpoints provide an additional layer of cell cycle regulation in case of damage