BIOL 2040 Study Guide - Midterm Guide: Petri Dish, Ames Test, Muller'S Morphs
Document Summary
Point mutation a mutation that results in the substitution of one nucleotide for. Synonymous(silent) mutation- point mutation that alters a codon but another, ak. a gene mutation does not change the a. a at that position (due to degeneracy of the genetic code) Nonsense mutation- a triplet is changed into a stop codon resulting in termination of translation of protein. Base substitution- a single base change in dna that produces a mutation. Transition a purine (a/g) is substituted for a purine; pyrimidine (c/t) Transversion - a purine is substituted for a pyrimidine or vice versa for a pyrimidine. Frameshift mutation - insertion or deletion of number of nucleotides (when number is not multiple of three), results in changing all (codons) amino acids after the insertion/deletion. The frame of triplet reading is altered during translation. Apurinic/apyrimidinic sites- a location on dna where neither a purine or pyrimidine base is present - can occur spontaneously or due to dna damage.