BIOL 1000 Study Guide - Midterm Guide: Dna Replication, Okazaki Fragments, Helicase
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Dna replication, cell division, cell cycle learning outcomes. Semiconservative replication: the process of dna replication in which the two parental strands separate and each serves as a template for the synthesis f new progeny double stranded dna. Dna polymerase: an enzyme that assembles the complimentary nucleotide chains during dna replication. Nucleotide triphosphates: is a molecule containing a nucleoside bound to three phosphate groups. Nucleoside triphosphates are necessary for life, as they provide the building blocks of nucleic acids (dna and rna) and have many other roles in cell metabolism and regulation. Ntps generally provide energy and phosphate groups for phosphorylation. The nucleoside triphosphates containing deoxyribose are called dntps, and take the prefix deoxy- in their names and small d- in their abbreviations: deoxyadenosine triphosphate (datp), deoxyguanosine triphosphate (dgtp), deoxycytidine triphosphate (dctp), deoxythymidine triphosphate (dttp) and deoxyuridine triphosphate (dutp). The dntps are the building blocks for dna replication (they lose two of the phosphate groups in the process of incorporation).
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