[Pharmacology 2060A/B] - Final Exam Guide - Ultimate 55 pages long Study Guide!
29 Mar 2017
School
Department
Course
Professor
Document Summary
Is defined the study of drug movement in the body. Is what the body does to the drug. x pharmacokinetics is composed of four basic processes: Over time dissolution occurs and the drug molecules are dissolved in the liquid. Pharmaceutical phase x the pharmaceutical phase occurs after the patient swallows a tablet. x x. It involves the disintegration of the tablet and the dissolution of the drug. If the drug does not completely disintegrate or does not go into solution, absorption is reduced. Enteric coating x drugs with enteric coating are covered with a special coating that prevents their dissolution in the acidic environment of the stomach. x once the drug passes into the more alkaline duodenum, the enteric coating dissolves. Bioavailability x bioavailability is the fraction of a dose of drug that reaches the systemic circulation unchanged. x bioavailability can be influenced by: drug formulation, route of administration, degree of metabolism, sublingual x.
