Biology 2382B Study Guide - Final Guide: Microtubule Organizing Center, Axoneme, Filopodia
19 Aug 2017
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Document Summary
25nm polymer of alpha and beta tubulin dimer subunits (8 nm). The positive end is the beta end of the protofilament. 13 protofilaments create a microtubule with a hollow center. Half life of about 5 minutes normally, 15 seconds during mitosis. alpha subunit beta subunit. One half of the microtubule dimer; binds permanently to gtp, (55 kilodaltons) One half of the microtubule dimer; hydrolyzes gtp (55 kilodaltons) protofilament. 10 protofilaments form a b-ring, as well as a c-ring microtubule organizing center; the area of nucleation for mts. Effectively caps the alpha end. a mtoc found in animals (contains centrioles) a nucleation center found in mtocs, made of triplet microtubules arranged in a ring; 2 barrels. Gamma tubulin nucleates polymerization, major protein in the mtoc. Ring complex, attaches to the alpha (-) end of mts pericentrolar matrix. Augmin complex found in pericentrolar matrix, part of ring complex; augment mt pericentrolar matrix. Flagella a 10-2000 micrometer method of movement for cells.
