BIOL 3070 Study Guide - Final Guide: Shiga Toxin, Endothelium, Exotoxin
8 Dec 2017
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Gi disease worksheet: the drug imodium (loperamide hcl) is an anti-diarrhoeal medication available in drugstores. In some cases of infectious diarrhoea, physicians recommend patients avoid using such drugs. List circumstances where these drugs would not be recommended, and why. In case of gastroenteritis (infectious diarrhea) as imodium slows down muscle contraction of the intestines and movement of food and fluid through the digestive tract, in result prolonging infection caused by viral pathogens such as norovirus and rotavirus. Diarrhoea associated with organisms that can penetrate the intestinal walls. In case of clostridium difficile infection as it increases risk of toxic retention and colon distension. People with liver failure due to reduced first pass metabolism normally, a drug is absorbed by the digestive system and enters the hepatic portal system. The liver metabolizes many drugs and reduces the concentration of the drugs before systemic circulation. This is reduced in case of liver failure or liver disease.
