CJH332H1 Study Guide - Comprehensive Final Exam Guide - Neuron, Wireless Access Point, Protein
Document Summary
Neurobiology of stress: stress is processed at the level of cerebral cortex, activating the medial prefrontal, anterior cingulate cortex, amygdala and hypothalamus (produces physiological response) Important in anxiety and depression: short term stress is good release of ne from locus coeruleus. Psychosocial stress (predator odor, elevated platform, social defeat or maternal separation: different circuits have different weakening effects. Affects on morphology/function: growing of neurons means an over- activation of the neurons (hypervigilant) after exposure to stress, dopaminergic neurons shrinks losing interest, hippocampus neurons shrinkage memory affected in bad way. Some individuals undergoing anxiety makes association with traumatic events (ptsd relation?) If corticosterone is elevated, it causes rapid glucocorticoid receptor-mediated increase of presynaptic snare protein complexes (mediates fusion of synaptic vesicles) in the presynaptic membrane. Why the complicated stress response: steroids can interact and cause genomic changes that are difficult to track in individuals.
