PSYC62H3 Study Guide - Midterm Guide: Pharmacodynamics, Alcohol And Health, Anterograde Amnesia
Document Summary
Alcohol produces depressant effects by inhibiting excitatory glutamate nmda receptors. Alcohol stupor: dulled senses & poor cognitive function. Blackout: reversible drug-induced dementia characterized by stupor. Alcohol poisoning: inhibition of autonomic system functions. Cardiovascular system: ischemia, stroke, heart attack, cardiac arrhythmias. Chronic alcohol administration increases number of nmda receptors. Alcohol increases serotonin concentrations in the nucleus accumbens. Al(cid:272)ohol"s phar(cid:373)a(cid:272)ologi(cid:272)al effe(cid:272)ts vary depe(cid:374)di(cid:374)g o(cid:374) al(cid:272)ohol"s (cid:272)o(cid:374)(cid:272)e(cid:374)tratio(cid:374) i(cid:374) the (cid:271)ody. Semantic memory ability to impair quality on hc & cerebral cortex w/ respect to gabaergic system. Acute tolerance: behavioral effects are weaker for declining bacs . Metabolic tolerance: increase in liver alcohol dehydrogenase enzymes. Sensitization to alcohol i(cid:374)(cid:272)rease i(cid:374) al(cid:272)ohol"s effi(cid:272)a(cid:272)y, espe(cid:272)ially its rei(cid:374)for(cid:272)i(cid:374)g effe(cid:272)ts. Dsm identifies two primary types of alcohol use disorders: Alcohol abuse: demonstration of the person engages in consumption of substance even though it creates negative impact on himself. Leads to severe & potentially life-threatening withdrawal symptoms. Alcohol withdrawal syndrome (hallucinations, trembling, confusion, disorientation, agitation)
