HLSC 2110U Study Guide - Midterm Guide: Bile Acid, Lecithin, Gallstone
23 Apr 2019
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Document Summary
Bile is made up of a watery mix of organic and inorganic compounds. Phosphatidylcholine (lecithin) and bile salts (conjugated bile acids) are the most abundant organic compounds. Bile is made in the liver and can pass directly to the duodenum from the bile duct or is stored in the gall bladder. 24 carbons, 2 or 3 hydroxyl groups, side chain that terminated in a carboxyl group. Act as emulsifying agents in the intestine help prepare tag and other lipids for degradation by pancreatic digestive enzyme. Bile acids are made in the liver by a multi-step path. Before bile acids leave the liver, they are conjugated to glycine or taurine by an amide bond between the carboxyl group of the bile acid and the amino group of the added compound. New structures are called bile salts glycocholic, glycochenodeoxycholic acids, taurocholic, taurochenodeoxycholic acids. More effective detergents than bile acids because of their amphipathic nature.
