PATH 205.3 Study Guide - Fall 2018, Comprehensive Midterm Notes - Necrosis, Epithelium, Thrombosis

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12 Oct 2018
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PATH 205.3
MIDTERM EXAM
STUDY GUIDE
Fall 2018
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L1 Introduction
Dr. Jay Kalra
Office: RUH G-3756 A
Phone: 655-2152
Objectives:
1. Brief introduction to Pathology and the Study of Disease
2. A review of medical nomenclature
Book: Pathology for the Health Professions 5th ed. by Ivan Damjanov
Exam:
Multiple choice
Short answer
Midterm: Oct 18 (40%)
Final: after Dec. 6 (60%)
Pathology = the science or study of disease
- The department of medical science, or of physiology, which treats the causes and nature of
diseases, or abnormal bodily affections or conditions
- A medical specialty which provides the scientific foundation for medical practice
Forensic Pathology = an important component of Pathology and makes a vital contribution to society
is clearly only a small part of the practice of most Pathologists
Pathologist/Laboratory Physician = a physician w/ a broad knowledge of medicine who works with all
other specialties, using the tools of laboratory medicine to provide information essential to problem
solving in clinical practice
- The edial detetie
Anatomical pathology
- Surgical
- Cytology
- Autopsy
Clinical pathology
- Hematology/blood bank
- Clinical chemistry
- Microbiology
Pathologist in patient care: in search of a diagnosis
Surgical pathology: cells and tissues in disease
- Fine Needle Aspiration
- Thyoid odule nucleus has a vacuole in it, has a large nucleus-to-cytoplasm ratio
- Breast lump larger cells & nucleus-to-cytoplasm ratio has increased compared to 1st slide
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Biopsy = the cutting out of tissue from a live person
- May be incisional (take a little bit) or excisional (take it all)
- Usually done to establish benign or malignant
- Sometimes establishes presence of infection
Autopsy, necropsy, post-mortem = dissection of a dead body to determine cause of death
- Hic Mortui Vivos Docere Amant (Here death delights to teach the living)
- Provides unique insight into the natural history of disease and the influence of therapy on
disease processes
- Pathologist assumes the role of educator y shaig the fidigs / the patiet’s physiia.
Together, they search for the lessons in each case that will benefit future patients
- Why do autopsies?
o Estalish the tuth
o 25% of clinical diagnoses may be completely or partially wrong
o Adds to knowledge of disease
o Important aspect of undergraduate and postgraduate teaching
- Contributions from autopsies:
o Relationship of blindness to retrolental fibroplasia
o Syndrome of metastasizing carcinoid
o Collagen diseases
o Radiation injury
o Post-radiation malignancy
o Hyperparathyroidism
o Potassium deficiency and lethal effects on myocardium and kidney
o New designs of seat belts
Coroners eas Co’s Ma
- Establishes who the deceased was, and where, when and how death occurred
- Coroner not required to have an MD in Saskatchewan, but may be required in other provinces
- Saskatchewan has a Chief Coroner
Investigates:
- Death from violence
- Known or suspected accident, suicide, or
homicide
- Death from criminal activity
- Deaths of persons in custody, such as
foster children, prisoners
- Deaths from negligence
- Unexplained deaths
Cooe’s Iuest is not:
- A trial
- A means of judgement
- A way of finding people guilty or innocent
Pathologists and Fire deaths
- Dental fillings may help identify a dead person
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Document Summary

Objectives: brief introduction to pathology and the study of disease, a review of medical nomenclature. Book: pathology for the health professions 5th ed. by ivan damjanov. Pathology = the science or study of disease. The department of medical science, or of physiology, which treats the causes and nature of diseases, or abnormal bodily affections or conditions. A medical specialty which provides the scientific foundation for medical practice. Forensic pathology = an important component of pathology and makes a vital contribution to society is clearly only a small part of the practice of most pathologists. Pathologist/laboratory physician = a physician w/ a broad knowledge of medicine who works with all other specialties, using the tools of laboratory medicine to provide information essential to problem solving in clinical practice (cid:862)the (cid:373)edi(cid:272)al dete(cid:272)ti(cid:448)e(cid:863) Pathologist in patient care: in search of a diagnosis. Thy(cid:396)oid (cid:862)(cid:374)odule(cid:863) nucleus has a vacuole in it, has a large nucleus-to-cytoplasm ratio.

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