BMSC 230 Study Guide - Final Guide: Emulsion, Citric Acid Cycle, Enoyl-Coa Hydratase
16 Dec 2015
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Document Summary
Are the most concentrated form of stored energy available to animals. 80% of energy requirements of the heart is from oxidation of fa. Insoluble in water, therefore can be stored in large quantities. Tg from intestinal cells blood (chylomicrons) tissues stored or oxidized. Chylomicrons: transport tg from intestine to tissues (liver, muscle, adipose) through circulation. Proteins: b-48: for removing the tg from the circulation. C ii: an activator of lipase enzyme, so the fa"s can be hydrolyzed, for them to cross the plasma membrane of the tissues. What happens to glycerol that"s cleaved off the 3 fa"s by the lipase: Glycerol (glycerol kinase) glycerol -3- phosphate dihydroxyacetone phosphate glyceraldehyde-3- phosphate glycolysis. To be oxidized, fatty acids need to be: activated (be bound to coa) once they enter the cell, transported (by carnitine shuttle): this transports fatty acyl coa across from cytosol to mito. Step 1: activation of fa to fatty acyl coa.
