PATH 3610 Study Guide - Final Guide: Von Willebrand Disease, Von Willebrand Factor, Oncotic Pressure

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Osmosis: the tendency of a solvent to pass from a solution of lesser conc. to one of greater solute conc. when the two solutions are separated by a semipermeable membrane. This drives uid back into blood vessels, carrying away the metabolic waste byproducts of the tissues (carbon dioxide, etc. ). Normally, the uid gains and losses between the arteriolar and venular ends of the capillary bed are balanced, such that the net gains and losses of uid from the vasculature are equal. The lymphatic vessels eventually drain into the bloodstream, so the uid does return, just not at the level of the capillary bed. The hydrostatic force at the venular end of the capillary bed would be increased. Thus, the uid remains in the tissue spaces as edema. With lymphatic obstruction, initially small amounts of uid will remain in the interstitium.

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