NUTR 4320 Study Guide - Final Guide: Mhc Class Ii, Inflammatory Bowel Disease, Tissue Transglutaminase
24 Dec 2016
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Recall: suggested that there had been asd epidemic other: gluten or wheat sensitivity. No immune reaction, different levels of intolerance, spectrum of symptoms untreated can be deadly no evidence that tolerance develops/can be induced. = no safe amount that you can be exposed to that won"t cause problems. What causes the disease? food antigen (gluten in this case) gluten = family of proteins, found in wheat but also in some greens. This is a dysregulated immune response to exogenous food antigens (dietary gluten) that results in significant inflammation and is transformed into an autoimmune-like reaction, similar to diabetes mellitus type i. This results in substantial damage to the structure and function of the gut and other organs. metabolism and target of therapy will be different destroys gi mucusa (not other organs) (destroy pancreatic b-cells) Text start to produce antibodies to your own proteins (not just bad ones)
