HK 4610 Study Guide - Midterm Guide: Achilles Tendon, Coxa Vara, Muscle Contraction

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24 Dec 2016
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Connective tissue: has characteristic features 1) specialized cells (ex. osteocytes), 2) extracellular protein fibers (ex. collagen), 3) fluid ground substance to fill space b/w cells/fibers. = extracellular matrix (ecm), greatest % by volume. Strength: 1) # crosslinks incr tensile strength to collagen, 2) alignment of tropocollagen (collagen fibres intertwine more links b/w fibres, the stronger the scar) Increased collagen production: 1) chronic inflammation (results in fibrosis), 2) re-injury (can be on sub-clinical level, before actual injury occurs: bad, want to minimize scar tissue, so therefore minimize collagen production. Recommend: low-load, long duration, sub-threshold force enhances collagen alignment long the lines of force loading. Connective tissue proper loose: 1. Location papillary region of dermis of skin and mucous membranes. Structure cells (fibroblast and wbcs), matrix (collagen and elastin, in fluid ground gel highly pliable in all directions b/c of elastin: 2. Function store energy, insulation, endocrine function, cushion vital organs, eyes, kidneys.