NU FS305 Study Guide - Final Guide: Selenium Deficiency, Chromium Deficiency, Manganese

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Selenium has antioxidant functions (glutathione, gsh, a tri-peptide of glutamate, glycine and cysteine converts looh loh + h2o) and is associated with a decreased risk of cancer. It also participates in the conversion of t4 to t3 (thyroid hormones). The rda is 55 ug/day and the ul is 400 ug/day. Depending on the soil concentration food sources such as vegetables and fruit may vary in containment. Selenium deficiency is a predisposition for keshan disease, a heart disease that affects the fibrous tissue. Toxicity symptoms include brittle hair and nails, rash, fatigue, irritability and garlic breath odor. The main function of manganese is to act as a cofactor for many enzymes in metabolic pathways that include macronutrient metabolism, bone formation and antioxidant function. The rda for men is 2. 3 mg/day and for women it is 1. 8 mg/day. Food sources include plant foods such as nuts, seeds and whole grains. Manganese absorption can be inhibited by high intakes of calcium an iron.

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