BIOL 205 Study Guide - Midterm Guide: Hfr Cell, Antimicrobial Resistance, Epigenome
13 Oct 2016
School
Department
Course
Professor
Document Summary
Genome- collection of all genes in an organism. Promoter can have mutations and still have 100% function. If there was a mutation in the intron where the spliceosome attaches to the intron, the intron could not be spiced making the entire gene null (non-functional) Forward genetics- starts with a variant phenotype and tries to identify the genetic differences. Reverse genetics- starts with a gene of unknown function and looks at what happens to the cells when you alter that gene. Properties that characterize genetic information: diversity of structure xn where x = # of nucleotides and n = # of base pairs, ability to replicate, mutability, translation into form and function. Drosophila eyeless gene needed to build eyes. Pax-6 is eye formation gene in humans: give a mouse with no eyes and see if her offspring have eyes. 2 normal alleles- tyrosinase uses tyr to produce melanin (normal skin tone)
