BIOL 103 Study Guide - Final Guide: Natural Killer Cell, Immune System, Epitope
24 Jul 2016
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Document Summary
Immune system: an animal body"s system of defences against agents that cause disease. Lymphocytes: b-lymphocytes: produced in bone marrow, t-lymphocytes: mature in thymus. Inflammation: innate local response to infection or injury: destroy or inactivate foreign invaders and clears area of dead cells and debris. Interferons: proteins that inhibit viral replication inside host cells, secreted into extracellular fluid: bind to plasma membrane receptors on secreting cell, synthesizes proteins that interfere with the ability of the viruses to replicate. Mediated b-lymphocytes (b-cells: b cells have membrane-bound antibodies on surface of membrane (immunoglobulins, each b-cell"s antibodies have different variable portions not the same as other b-cell"s, epitope: area of pathogen"s surface that binds to a specific b-cell. Immunoglobin (antibody) protein family: each composed of 4 polypeptides, 2 long heavy chains, 2 short light chains each of two branches can bind to epitope of pathogen, 2 pathogens per 1 antibody.
