IMED3001 Study Guide - Quiz Guide: Aorta, Renal Artery, Blood Vessel
20 Dec 2020
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May affect arteries, veins or capillaries. Most of the time, immune mechanisms are to blame. Deposition of immune complexes, activating the complement cascade. Direct attack on vessel wall by circulating antibodies. Blood vessel inflammation can be seen in a variety of settings. Aetiology eg. syphilitic aortitis is caused by an infection. Size of the vessel affected see robbins, ch 11, p506 (9th ed) Location of the vessels affected eg cutaneous vasculitis. Large vessels (aorta and large arteries) Small vessels (arterioles, capillaries, venules, veins) Buerger"s disease, drug induced, infectious, others. Inflammation of large and medium size arteries. Usually involves branches of the carotid artery, especially the temporal artery. Gold standard for diagnosis is biopsy of the temporal artery. A multisystem necrotising vasculitis involving medium sized arteries. Classically involves the renal arteries and the mesenteric arteries. Can also involve the heart, liver, skin.
