IMED3001 Study Guide - Midterm Guide: Lamina Propria, Stratified Squamous Epithelium, Bronchiole
14 Dec 2020
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Document Summary
Non-ciliated cells with dome-shaped apical surface, predominantly present in the bronchioles. Produce surfactant-like substance, share functional similarities with type ii pneumocytes. Secretion of antimicrobial peptides for local immune defense. The cilia lose their synchronous beating pattern as a result of toxic elements in tobacco. In smokers, respiratory epithelium may alter to stratified squamous epithelium. To compensate, the individual begins to cough, thereby facilitating the expulsion of accumulated mucus. Metaplastic epithelium may undergo malignant transformation, squamous cell carcinoma. The bronchial tree consists of branched airways leading from the trachea to the alveoli. The successive divisions of the branches from the trachea to the alveoli are: Right and left primary bronchi secondary/lobar bronchi. 2 lobar bronchi in the left and 3 in the right lung. 10 segmental bronchi in right lung intralobular bronchioles. Nearly have the same structure as the trachea. Layer of smooth muscles between the lamina propria and submucosa. Epithelium becomes less stratified with less goblet cells.
