NEUR3101 Study Guide - Final Guide: Squid Giant Axon, Pacemaker Current, Pipette
Document Summary
Understand that dendrites of neurons contain a variety of voltage-activated channels, which can impact on their electrical properties (focus on hcn channels) Understand that activation of voltage-activated channels in dendrites can lead to generation of a range of regenerative events, such as sodium, calcium and nmda spikes. Understand how the active properties of dendrites influence and enrich the computations that neurons can perform on their synaptic inputs. Voltage gated channels give active properties to cells. Ir-drc allows visualisation of processes of neurons, so can approach them with a patch- pipette. Just recording from channels under that part of membrane. Amplitude of inward current conserved across dendritic membranes after about. 1mm -> means that there are sodium channels in dendrites. Impacts on electrical properties of dendrites, not unlike the impact they have of the axons of neurons (critical there for propagation of aps) Like a delayed rectifier current you see in the squid giant axon - don"t inactivate.
