NEUR3101 Study Guide - Final Guide: Depolarization, Peptide, Lipid Bilayer

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12 Jan 2020
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Specific ion channels (like na+ channels or k+ channels) Monovalent cation selective channels (like ones that will allow all ions with 1 valence e- pass through) Recall: self-limiting channels (close even when membrane remains depolarised) Be familiar with the properties of the "toolbox" of common ion channels (vg-channels, ca- activated channels, ligand-gated cation channels, ligand-gated anion channels) Potassium channel of which is activated by the presence of ca2+ First part is the name of the agonist = thing that binds to open the channel. First part is the name of the agonist. Single poly-peptide channel with 4 homologous domains (i-iv) -> separate subunits all of which are a part of a giant peptide. Act in a similar way to other channels of which are comprised of multiple subunits. Voltage sensor -> positively charged aa residues that detect the field, or the gradient across the membrane and will twist the channel to open it.