Answer the following question:

1. In your own words, explain why, if two compounds have the same LD50 value, they aren’t necessarily as toxic. Make sure to include the term Threshold in your answer. 

 

 

Answer the following questions:

1. Describe the experiments that need to be done in order to determine the LD50 and what a chart would look like (sketch this out and label axes and important points)

1. An LD50 value is the best measure available to indicate the potential for a compound to cause harm, to be toxic. However, there are six limitations that we looked at and explained. Below, using your own words, name each of these limitations and explain in detail (and with an example/scenario if possible) why it’s a limitation.

1. An LD50 value is the best measure available to indicate the potential for a compound to cause harm, to be toxic. However, there are six limitations that we looked at and explained. Below, using your own words, name each of these limitations and explain in detail (and with an example/scenario if possible) why it’s a limitation.

answer the following questions:

1. When you are exposed to more than one compound, one of the following can be observed: (1) Additive, (2) Synergistic, and (3) potentiation. Define each term and give an example using values or a bar chart. 
2. Define and distinguish sensitivity, tolerance, and resistance with respect to exposure to a compound.
3. Define LD50
4. Why is it that the lower an LD50, the more toxic it is?