CHEM 2323 Study Guide - Midterm Guide: Epoxide, Acid Dissociation Constant, Halohydrin
Document Summary
Many of these reactions are review from previous chapters (8, 10, 11), with only a few reactions being something you have not seen before. Ethers are generally unreactive, commonly used as solvents for reactions, so there are very few reactions that occur with them. With epoxides, keep in mind the stereochemistry and regiochemistry of the product! I have underlined the reaction name for the reactions you need to know, and bolded the reaction name that you need to know the mechanism for! An ether is formed by extracting a hydrogen is from an alcohol using a base,(nah is commonly used, naoh can be used as well), forming an alkoxide. The resulting alkoxide ion then reacts as a nucleophile, attacking an alkyl halide, forming the ether. Reactant- alcohol (can be either 1o, 2o, or 3o) Reagent a strong base (na+), and then any electrophile (alkyl halide) Know the entire mechanism and reagents used!
