BSCI 1511 Lecture 3: BIO1511 HORMONAL SIGNALING

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Negative in secretin- negatively regulates s cells to make them stop secreting secretin- secretin hormones released from s cells in response to low ph into blood and target cells in pancreas which release bicarbonate (which raises blood ph) Milk causes baby to suckle more (positive feedback) and pathway continues until baby stops suckling. Baby suckles, stimulating sensory neuron which stimulates a neurosecretory cells, which secrete neurohormones (oxytocin) Oxytocin travels thru blood to target cells in smooth muscle mammary. Hormone cascade (thyroid hormone) glands which release milk. Neurohormone travels thru blood to target endocrine cells and bind to receptor causing release of another hormone and so on. Receives info from nerves and initiates endocrine signaling. Hormonal signals from hypothalamus travel to pituitary gland (2 fused glands. Posterior is an extension of hypothalamus and neurons from hypothalamus reach into posterior pituitary and secrete neurohormones from hypothalamus. Anterior secretes hormones in response to hypothalamic hormones. Thyrotropin releasing hormone trh from hypothalamus causes ant.

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