BIOL 522 Lecture Notes - Lecture 6: Effective Population Size, Introgression, Haplotype
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Main goals: refine estimates because many different explanations/ theories. S1: where samples are from, count of heterozygous sites, distance from addis ababa (eastern africans) - decrease diversity because modern humans originated in africa - correlation between distance from. D stats = cohen"s d in statistics - the expected difference between the means between an experimental group and a control group, divided by the expected standard deviation. It is used in estimations of necessary sample sizes of experiments. Southeast asians (eg. papua) and native americans have high admixture with altai neanderthals and denisovans. Areas with high conservation, higher ratio of ti/tv because transition is less likely to affect function. S10: maybe xooa introgressed with neanderthal, which already had some admixture with humans. : beige pieces are admixtures, ordering doesn"t matter/ not a timescale. Msmc you have different groups and look at first individuals from different groups, you only look for first coalescence activity between them to look for first common ancestor.
