BIOS 101 Lecture Notes - Lecture 12: Cell Surface Receptor, Lipid Bilayer, Low-Density Lipoprotein
Document Summary
Structure and function of cell membranes, composition= mosaic of macromolecules i. ii. 2 layers phospholipids: hydrophilic polar heads point outward forming h bonds with h2o, hydrophobic non polar fatty acid tails point inward iii. iv. v. vi. vii. Cholesterol (animal cell membranes only) embedded in phospholipid bilayer glycoproteins= sugars often attached to the proteins glycolipids= sugars often attached to the phospholipids. All organelle membranes have similar structure as cell membrane: for membranes to function they must be fluid; phospholipids can move, functions of cell membrane proteins, some cell membrane proteins are cell surface markers= glycoproteins i. Identify or label each type of cell: ex: human rbc"s have glycoprotein surface markers referred to as a,b, and ab blood type ii. Important in tissue transplants: some cell membrane proteins are cell surface receptors, ex: ldl cholesterol receptors, insulin receptors ii. iii. Cell surface receptor proteins have shapes that fit the shape specific messenger molecules.
