MCD BIO 165A Lecture Notes - Lecture 16: Inner Mitochondrial Membrane, Atp Synthase, Granulosa Cell
10 Jan 2019
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Interconnected (green) throughout the cell (red is er: mitochondria: characteristic morphologies despite variable appearance. Typical mitochondria are bean-shaped, but may be round/threadlike. Size and number of mitochondria reflect the energy requirement of cell. Large majority of proteins required for mitochondria survival coded by nucleus; transcribed & translated in cytosol & imported into mitochondria. Atp synthase anchored on inner membrane, particularly on cristae; protrudes into mitochondria matrix. Amount of cristae -> how much oxidative phosphorylation may have. E. g. oogenic cell mitochondria has cristae, but not as much as muscle cell. Has a circular dna molecule, ribosomes, enzymes. Similar to bacteria: plasmid-like dna, enzymes exclusively in bacteria & mitochondria. Enzymes made in cytosol & imported into mitochondria. Rna and proteins can be synthesized in matrix. Has ribosome (no other organelle has) anchored in cristae (makes transmembrane protein in cristae) or loose in matrix (present as polysomes when.
