MCD BIO 165A Lecture Notes - Lecture 10: Endomembrane System, Cell Membrane, Hemidesmosome

• School: UCLA
• Department: Molecular, Cell, and Developmental Biology
• Course: MCD BIO 165A
• Professor: arispe

Document Summary

Endomembrane system: made up of all the system involved in production, modification & trafficking of proteins, greater complexity & efficiency for euka(cid:396)yoti(cid:272) (cid:272)ells (cid:894)p(cid:396)oka(cid:396)yoti(cid:272) (cid:272)ells do(cid:374)"t ha(cid:448)e those(cid:895) Cells involved in steroid production, detoxification have lots of smooth er. Drug processing & elimination: making insoluble drugs soluble by adding hydroxyl -> processed & eliminated thru kidneys. Hepatocytes (liver cells) important in breaking down ethanol & detoxification. Hepatocytes also has lots of rough er visualize. Disulfide isomerase (resident in er) specific for rough er: chaperone for protein folding.