BIO 112 Lecture Notes - Lecture 4: Hugo De Vries, Gustav Tschermak Von Seysenegg, Heredity
9 Sep 2015
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His controlled so have been crossing round peas with round peas and wrinkled peas with wrinkled peas. F1 generation crossed with f1 generation = 3:1 ratio. Mendel"s hypothesis: that there were some laws governing inheritance; different pieces of information are sometimes manifested in the phenotypes and sometimes not. Hugo de vries, karl correns, erich von tschermak discovered and understood mendel"s paper. Sir archibald edward garrod: applied mendelism to humans, determined that. Alkaptonuria was a recessive trait and first demonstrated that diseases were inborn errors of metabolism and mendel"s laws apply to humans. Reginald punnett and william bateson: tried to sell mendelian laws; discrete characters, we can use mendel laws. Mendelian says that you have distinct and discrete characters. Walter weldon: did not agree with mendel laws, supported blending inheritance, continuous characters/phenotypic distributions. Brca1 obeys mendelian inheritance but the phenotype is more complicated because of environmental factors as well as the fact that there are multiple genes/genetic background.
