BIO 211 Lecture Notes - Lecture 29: Sphincter Of Oddi, Pancreatic Juice, Intestinal Gland

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Regulation of secretion of pancreatic juice and bile. Acetylcholine (ach) - from vagus and enteric nerves. Stimulates acini to secrete their enzymes during the cephalic phase of gastric control even before food is swallowed. Enzymes remain in acini and ducts until chyme enters the duodenum. Cholecystokinin (cck) - secreted by mucosa of duodenum in response to arrival of fats in small intestine. Induces contractions of the gallbladder and relaxation of hepatopancreatic sphincter causing discharge of bile into the duodenum. Secretin - released from duodenum in response to acidic chyme arriving from the stomach. Stimulates ducts of both liver and pancreas to secrete more sodium bicarbonate. Raising ph to level pancreatic and intestinal digestive enzymes require. The segment of small intestine closest to stomach. Mixing bowl that receives chyme from stomach and digestive secretions from pancreas (trypsinogen, chymotrypsinogen, procarboxypeptidase, amylase, lipase, ribonuclease, deoxyribonuclease) and liver (bile). Functions of the duodenum produces copious amounts of mucus.

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