BIOL 190 Lecture Notes - Lecture 5: Keratinocyte, Sodium Chloride, Glycocalyx

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12 Oct 2016
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Adjacent cells in many animal tissues are often directly connected by cell junctions consisting of specific proteins. For a water - tight seal between the two membranes. Prevent passage of material between the cells. Common in epithelial cells- cells that line cavities and organs. Example: in intestinal epithelial, tight junctions prevent the passage of gut content between cells that line the gut. Connect the cytoskeletons of adjacent cells (desmosome) May also anchor a cell"s cytoskeleton to the ecm. Provide mechanical strength to the tissue by connecting many. Example: between keratinocytes in the skin epidermis, where the multiple layers of dead but firmly connected keratinocytes form the barrier that separates you from the environment cells firmly together. Form pores that provide direct connection between the cytoplasm of adjacent cells. Allow flow of small molecules and ions from one cell to the next. Permit communication between adjacent cells that coordinate the tissue"s reaction to stimuli. Made up of phospholipids, proteins, chos, cholesterol.

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