VTPB 405 Lecture Notes - Lecture 18: Hand, Foot, And Mouth Disease, Coxsackievirus, Dilated Cardiomyopathy
16 May 2020
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Coxsackie a mouth disease hand foot red vesicular rash aseptic meningitis dilated cardiomyopathy. Naked inhalation acid labile fomites attaches to icam i. Cool 33 c upper respiratory tract can"t go through gl enter host many diff serotypes supportive treatment. Negative sense rna must bring own rna polymerase. Influenza a b c replicates in nucleus enveloped. Antigenic unique segments drift shift f10 point mutation re assortment of segments pandemic seasonal. Hi h2 h 3 etc determines tropism anti ha antibodies. Neuraminidase spread via respiratory droplets dec feb around oct killed 1m or intranasal oseltamivir. Na cleaves sialyc acid to release virions pneumonia. Guillain barre syndrome ltprotein d wbc common complication. Paramyxovirus attenuated vaccine not in pregnant e replicate in cytoplasm single strand 0 sense rna enveloped respiratory droplets. Ru a measles runny nose cough coryza conjunctivitis. Maculopapular n starts on confluent rash few days later face and moves rash down pneumonia encephalitis subacute sclerosinspan encephalitis.
