BIO-1 Lecture Notes - Lecture 16: Nucleolus, Actomyosin Ring, Cytokinesis
Document Summary
Mitosis process of division of nucleus and its contents (dna) Cytokinesis rest of the cytoplasm gets divided. 1-prophase (& prometaphase) lamins by m-cdk-cyclin the er centrosomes migrate to opposite ends of the nucleus forming a bridge between the 2 mtoc (interpolar microtubules) Cell has passed the g2/m checkpoint and is committed to division. At end of prophase nuclear envelope breaks down due to phosphorylation of nuclear. When nuclear lamina breaks up, the nuclear envelope breaks up into pieces, along with. During prophase the spindle develops to form microtubules associated with the. Prophase precedes the centrosomes with their associated microtubules separate and. Formation of mitotic spindle relies heavily on the dynamic instability of the microtubules. New microtubules grow and shrink at random from each mtoc. If 2 mt happen to interact, they will stabilize each other with the help of motor proteins, However, if they happen to interact with kinetochore during random growth and.